Friendship of Kaley Cuoco and Zosya Mamet

The Stewardess begins as a romance that quickly deteriorates due to a night of alcohol-fuelled fun that leads to a gruesome unsolved murder. At the heart of the show, which touches on everything from alcoholism to espionage, is a love story defined not by Cassie (Kaley Cuoco) and her one-night stand Alex (Michiel Huisman), but by Cassie and her on-screen best friend Annie. (Zosya Mamet). When filming began in 2019, their chemistry was second to none. Two years later and just as many identical tattoos, best friends are inalienable proof that good things can come out of hard times.

How Kaley Cuoco and Zosia Mamet met

While casting for The Flight Attendant, Cuoco and Mamet were asked to read chemistry together, a hypothetically difficult task that solidified their work and their friendship. Michelle [Huisman] and Kaylie’s relationship, it’s totally a love story, but a true love story [‘The Flight Attendant’] it’s Annie and Cassie,” Mamet said. Hollywood Reporter in June 2021. “When I heard that they wanted me [do a] was reading chemistry with Kaylie, I thought, “Oh, they see how important this relationship is”; you need to read the chemistry between two female best friends who have been best friends since childhood.”


“It was an immediate spark of chemistry between the two of us.”

The read chemistry was a success as it allowed both actors to become best friends on screen and laid the foundation for a years-long friendship. “I walked into this room and they said, ‘Feel free to play,'” Mamet said. “I was pretending to be on the phone in the audition room and Kaylee came up and punched me in the nose, which wasn’t in the script, and I immediately pushed her hand away, saying, ‘Don’t do it. I always say it [and] at this point, Annie and Cassie were born. It was an immediate spark of chemistry between the two of us. . . We both have a great sense of the game and we love working together. I think we were the bane of our first [assistant director’s] existence, because they literally had to say, “OK, stop. Stop, we said cut! We just had so much fun together.”

Kaley Cuoco and Zosia Mamet as Roommates

On set, Cuoco and Mamet, whose on-screen characters are more serious than goofy, take turns making each other laugh, breaking away from the script and showing affection in the form of hugs and countless “ups.” The unprecedented bond between friends grew even stronger when Cuoco split from her husband of three years, Karl Cook, in September 2021.

Conversation with Kelly Clarkson on “The Kelly Clarkson ShowOn April 28, Cuoco revealed that Mamet moved in with her shortly after her divorce to help her deal with her emotions, adding that she found it hard to open up at first. “I tried to take everything on myself until I realized. In fact, I physically couldn’t do it anymore,” she said. Zosya is my co-star and my best friend. She basically lived with me for the last few months of filming (Season 2), we had just moved in together and I don’t think I could have worked a few days without her. . . I never thought that I had to be so dependent on someone before, and I was really dependent on her. She helped me get through a lot.”

“Obviously, romantic relationships are important, but I think female friendships take them to the next level.”

A roommate turned out to be exactly what Cuoco and Mamet needed to solidify their friendship, and this act of selflessness left a lasting impression on Cuoco. “She came to work on days when she didn’t need to be there and came to have lunch with me,” she said. “I’m like, ‘It’s your day off,’ and she’s like, ‘I’ll be there,’ because she heard that I had a hard time, and she’s going to sit in my trailer. She is the best. I’m very lucky to have her.”

In the same interview, Mamet explained that their friendship is unmatched. “I’m not very close to my family and I’ve always considered my chosen family extremely important,” she said. “I think like women [that friendship] is equivalent to anything. Obviously, romantic relationships are important, but I think female friendships take them to the next level.”


Friendship of Kaley Cuoco and Zosya Mamet

More recently, the friends have gone all over Instagram, posting heartfelt birthday wishes to each other, as well as carousels of photos to take a look behind the scenes of their adorable friendship. “HAPPY BIRTHDAY to this magical human unicorn,” signed Mamet. Instagram Cuoco post November 30, 2021 “You are one of a kind @kaleycuoco, I love you more than words can express. Here’s another thousand years of adventure and laughter together, so much that our abs hurt. You will always be Cassie to my Annie.”

In response, Cuoco shared a tribute to Mamet’s birthday on February 2. “Happy birthday to the unicorn fairy princess who is @zosiamamet!!” she wrote. “I am so grateful that you danced in my life and never left. You deserve the whole world. Kind, funny, sweet, empathetic, charming, genius image in you really touches everyone you meet. I’m not sure what my life would have been like in the past few months if you hadn’t told me to go to work and that everything would be fine… I love you forever sister wife. !! 🎂 🎈 💋 🎁 you will always be Annie to my Cassie! Boop!”


As a nod to their friendship and “flight attendant,” Cuoco and Mamet got matching paper airplane tattoos together in October 2020. the honor of their meeting is dear.

Cassie and Annie may be willing to help each other get away with murder, but Cuoco and Mamet’s true friendship is the real deal. See more high-profile photos of best friends, including their time at the tattoo parlor, ahead.

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